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Some side effects of taking RYTARY including sleepiness and dizziness may affect your ability to drive or operate machinery.

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Talk to your healthcare provider before you lower the dose or stop taking RYTARY, as this may result in serious side effects.

Call your healthcare provider immediately if you develop withdrawal symptoms such as fever, confusion, or severe muscle stiffness.

Make sure to tell your healthcare provider if you have any heart conditions, especially if you have had a heart attack or experience irregular heartbeat.

Some people with a history of or risk factors for heart disease have experienced heart problems while taking RYTARY.

Do not take RYTARY with antidepressant medications known as nonselective monoamine oxidase (MAO) inhibitors because taking these two drugs within two weeks of each other can result in high blood pressure.

Taking RYTARY may result in falling asleep while engaged in normal activities, even without warning and as late as one year after starting to take RYTARY.

See your healthcare provider for regular skin examinations when taking RYTARY.

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